Whatley previously met with National Republican Senatorial Committee Chairman Tim Scott about a potential Senate run in North Carolina, and the NRSC had been floating Whatley as a possible replacement for Tillis since January, according to a GOP operative. Tillis did not announce his plans to not seek re-election until months later.

President Donald Trump's daughter-in-law Lara Trump on Thursday said she would not run for the U.S. Senate in North Carolina next year, setting the stage for an expected matchup of former Democratic Governor Roy Cooper and Republican National Committee Chairman Michael Whatley.