For years, the pancreas has been being taught in biology class as an easy system: insulin lowers blood sugar, and glucagon raises it. But that’s much too simple, new research says. Scientists at Duke ...
Mor than 800 million people worldwide are living with diabetes, according to World Health Organization (WHO) estimates, with numbers steadily increasing. Diabetic patients experience abnormally high ...
A new study from Duke University School of Medicine is challenging long-standing views on blood sugar regulation—and pointing to a surprising new ally in the fight against type 2 diabetes. Subscribe ...
Duke University scientists have discovered that pancreatic alpha cells, long believed to only produce glucagon, actually generate powerful amounts of GLP-1 — the same hormone mimicked by popular ...
Recently, Quinn Peterson and colleagues from Mayo Clinic, USA, discovered a method for making human alpha cells from cultures of immature stem cells. This work was recently published in Stem Cell ...
In recent years, effective obesity treatments like Ozempic and Mounjaro have changed lives. These drugs mimic the effects of a hormone called GLP-1, which normally influences insulin levels and helps ...
Glucagon was discovered in the early 1960s and is a potent insulin secretagogue. It is a 29 amino acid polypeptide, and its secretion is regulated directly by amino and free fatty acids and indirectly ...
A team of diabetes and obesity researchers led by Jonathan Campbell, PhD, at the Duke University School of Medicine, shows alpha cells in the pancreas unexpectedly churn out potent, insulin-boosting ...