Memantine (sometimes sold under the brand name Namenda) is an oral medication that blocks the brain's receptors for glutamate ...

New research shows that psilocybin, the active compound in psychedelic mushrooms, can reduce both chronic pain and pain-related depression by modulating brain circuits rather than acting at the site ...

Penn researchers found that psilocybin can calm brain circuits tied to pain and mood, easing both physical suffering and ...

Neurons selective to running trajectories in the rat anterior cingulate cortex are reactivated during observation and interact with hippocampal replay to guide subsequent spatial navigation.

Closed-loop targeted deep brain stimulation holds promise in addressing symptoms of depression and obsessive-compulsive ...

Researchers at Penn Medicine have identified specific brain circuits that are impacted by psilocybin—the active compound ...

Penn Medicine researchers discovered that psilocybin can ease chronic pain and depression by subtly tuning serotonin activity in the brain.

However, it's difficult to pin down exactly what's causing this boost in gray matter. Another possibility raised by the researchers is that the rose scent is actually labeled as unpleasant by the ...

Why do we get distracted? Whether you're trying to hold a conversation at a busy restaurant or read on a crowded train, our brains sometimes struggle to pay attention. And while that might be annoying ...