In the past decade, nucleic-acid-based drugs have become firmly established as a therapeutic modality. Drugs in two classes have now reached the market for multiple diseases—antisense oligonucleotides ...

This improved technological platform can be used to develop new treatments, molecular diagnosis strategies or vaccines for various diseases. Research has shown that some nucleic acids, such as ...

The unique applications of nucleic acid aptamers and their expanding properties across various sectors is fueling the nucleic acid aptamers market growth. Aptamers are being explored in drug delivery ...

Entos Pharmaceuticals’ star is rising. Just a few short months after the biotech’s nucleic acid delivery tech helped land a deal with BioMarin, the Edmonton, Alberta-based Canadian company has teamed ...

This study addresses endosomal escape in oligonucleotide therapies and how engineered peptides can enhance intracellular drug delivery efficiency.

DNA, the blueprint of life, is best known for its fundamental role as genetic material—storing and transmitting biological information through the precise sequence of its bases. For decades, this ...

WEST LAFAYETTE, Ind. — A researcher in Purdue University’s College of Science is developing a patent-pending platform technology that mimics the dual-layer structure of viruses to deliver nucleic acid ...

A consortium featuring AstraZeneca has secured funding to advance the delivery of nucleic acids, teeing the collaborators up to create new methods for getting oligonucleotide therapies to target ...

DNA is the poster child for high-specificity binding. As long as their base sequences match, two complementary strands of DNA can navigate through a sea of biomolecules, find each other, and hold fast ...

Harnessing surface engineering strategies to functionalize nucleic acid-lipid nanoparticles (LNPs) for improved performance has been a hot research topic since the approval of the first siRNA drug, ...

A researcher is developing a patent-pending platform technology called LENN that mimics the dual-layer structure of viruses to deliver nucleic acid (NA)-based therapies to targeted cancer cells. A ...