Efforts to foster both intrinsic and extrinsic regenerative responses in heart failure have once again brought iPS cell technologies to the forefront, thanks to their flexibility in reconstructing ...

A process using human stem cells can generate the cells that cover the external surface of a human heart — epicardium cells — according to a multidisciplinary team of researchers. "In 2012, we ...

Medical researchers have found that a key to the zebrafish's ability to regenerate cardiac tissue lies in the outer layer of the heart known as the epicardium. When this critical layer is damaged, the ...

Whether there are endogenous adult heart progenitors that can replenish damaged muscle cells remained controversial. Now researchers at Karolinska Institute in Sweden show that the outermost layer of ...

Heart disease remains the leading cause of death in the world. One reason is that unlike other tissues, such as bone and skin, the heart has remarkably poor regenerative capability after an injury ...

A study revealed that the neurohormone oxytocin induces epicardial cell proliferation, which is vital in forming Epicardium-derived Progenitor Cells (EpiPCs). A function of oxytocin discovered in a ...

Summary: Researchers show for the first time that the neurohormone oxytocin has a previously unsuspected function in both zebrafish and human cell cultures: it stimulates mature cells in the ...

CHAPEL HILL, N.C. – After a heart attack, the portions of the heart damaged by a lack of oxygen become scar tissue. Researchers have long sought ways to avoid this scarring, which can harden the walls ...