In some people who carry a repeat expansion in the C9ORF72 gene, methylation of the gene promoter shuts down its transcription. This offers a modicum of protection against amyotrophic lateral ...

Although amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). are very different diseases, they have ...

This open-label Phase 1 study measures safety, peripheral and central inflammation, effects on Treg cell populations, and FTD progression; Five of the 8 planned FTD subjects have been enrolled to date ...

Transition Bio and Voyager have teamed to discover and develop new small molecules that target toxic TDP-43 protein clumps in ...

"Vesper Bio’s FTD candidate shows progranulin increase in Phase Ib/IIa trial" was originally created and published by Clinical Trials Arena, a GlobalData owned brand.

Passage Bio, Inc. announced interim results from its PBFT02 clinical trial for frontotemporal dementia (FTD) patients with the GRN mutation, revealing significant increases in cerebrospinal fluid (CSF ...

How can apathy be managed in an individual with frontotemporal dementia? Frontotemporal dementia or frontotemporal ...

Recent research from the University of Eastern Finland revealed increased inflammatory activity in a subgroup of patients with frontotemporal dementia (FTD). Increased inflammation was associated with ...

Beloved “Die Hard” and “Moonlighting” actor Bruce Willis has been diagnosed with frontotemporal dementia, or FTD, his family revealed on Thursday, which is the most common form of dementia in people ...

Interim results from Part A in healthy volunteers demonstrated dose-dependent increases in CSF progranulin levels, consistent with robust brain delivery of DNL593 Single doses of DNL593 were generally ...

Results of study will inform Coya’s randomized, double-blinded Phase 2 trial of COYA 302 in patients with FTD Coya Therapeutics, Inc. (NASDAQ: COYA) (“Coya” or the “Company”), a clinical-stage ...