Probenecid (Benemid) is a uricosuric agent that inhibits the reabsorption of uric acid in proximal tubules of the kidney. 36 Pharmacologic therapy typically begins at 500 mg b.i.d. and gradually ...

When you think of arthritis, achy, warm, swollen joints probably come to mind. These are indeed some of the most common symptoms of arthritis. But did you know there are actually over 100 different ...

gout of foot The investigational drug AR882 appeared more effective and safer than allopurinol monotherapy in a phase 2 trial. A novel selective URAT1 inhibitor, AR882, further reduces serum uric acid ...

Full results from the so-called MIRROR trial have now been published and suggest the FDA made the right decision this summer to approve methotrexate as an add-on to pegloticase (Krystexxa) for ...

In a recent study published in the BMC Musculoskeletal Disorders, researchers performed a systematic review and meta-analysis to explore the effects of nanoparticles on gouty arthritis using animal ...

Over the years, gout has grown in clinical complexity. We see many more cases with iatrogenic factors, multiple comorbidities, advanced age and treatment-refractory hyperuricemia and arthritis (Table ...

The study revealed how a second drug taken orally more than doubled the effectiveness of Pegloticase, an intravenous gout treatment used to dissolve crystalized uric acid in the joints when oral ...

TOKYO, Jul 14, 2025 - (JCN Newswire) - - Eisai Co., Ltd. (Headquarters: Tokyo, CEO: Haruo Naito, "Eisai") announced today that it has launched "URECE" (brand name in China: "Youlesi", generic name: ...

Malik, Schumacher, Dinnella, and Clayburne compared the sensitivity and specificity of the above criteria with synovial-fluid analysis. 18 Results showed the following predictive values: Rome, 76.9%; ...