The actress, whose new memoir is out next month, jokes that she rates the disease "zero stars," adding, "Would not recommend" ...

The actress says multiple sclerosis exhaustion is often misunderstood, and far more debilitating than people realize.

Jamie-Lynn Sigler is the latest celeb to chop it all off. The actress just went to makeover queen Riawna Capri to rid herself ...

Jamie-Lynn Sigler, who lives with multiple sclerosis, co-starred in an episode of Grey's Anatomy as a doctor with MS Sigler, 44, says that the role was created specifically for her — and for the first ...

The actress said she decided after having two boys that she didn't want to have a third due to MS "I can tell you, having been a mom of young kids [and having] MS, I see your pain and your struggle.

From 'The Sopranos' to 'Grey’s Anatomy,' the actress shares how living with MS has made her a more present parent and powerful advocate.

Martin Holmes, TV Insider Dec 12, 2025 Dec 12, 2025 Sigler confirmed her Grey’s Anatomy casting on Instagram on Thursday (December 11). “If you told me 20 years ago that I would play a role on one of ...

After a three-year break from television, The Sopranos actor Jamie-Lynn Sigler is returning to the small screen in an important new guest role on ABC’s Grey’s Anatomy. According to Deadline, Sigler ...

Former "Sopranos" star Jamie-Lynn Sigler, a Jericho native who in 2016 revealed she had been battling MS for 15 years, will play a doctor with that disease in the Jan. 15 episode of ABC’s long-running ...

'Deadline' reported that the role was created for Sigler, who was diagnosed with MS in 2002 Gary Miller/Getty Images Jamie-Lynn Sigler is joining the Grey's Anatomy cast! The actress, 44, revealed to ...