The actress, whose new memoir is out next month, jokes that she rates the disease "zero stars," adding, "Would not recommend" ...

The actress said she decided after having two boys that she didn't want to have a third due to MS "I can tell you, having been a mom of young kids [and having] MS, I see your pain and your struggle.

Jamie-Lynn Sigler, who lives with multiple sclerosis, co-starred in an episode of Grey's Anatomy as a doctor with MS Sigler, 44, says that the role was created specifically for her — and for the first ...

From 'The Sopranos' to 'Grey’s Anatomy,' the actress shares how living with MS has made her a more present parent and powerful advocate.

Martin Holmes, TV Insider Dec 12, 2025 Dec 12, 2025 Sigler confirmed her Grey’s Anatomy casting on Instagram on Thursday (December 11). “If you told me 20 years ago that I would play a role on one of ...

Former "Sopranos" star Jamie-Lynn Sigler, a Jericho native who in 2016 revealed she had been battling MS for 15 years, will play a doctor with that disease in the Jan. 15 episode of ABC’s long-running ...

After a three-year break from television, The Sopranos actor Jamie-Lynn Sigler is returning to the small screen in an important new guest role on ABC’s Grey’s Anatomy. According to Deadline, Sigler ...