Researchers have revealed the structure and function of a previously unknown lysosome transporter. The groups of Christian Löw (CSSB, EMBL Hamburg), Markus Damme (Christian-Albrechts-University Kiel), ...
Inside every human cell, a tiny structure called a lysosome acts like a recycling center, breaking down toxic waste, clearing ...
mTORC1 promotes cell growth by sensing nutrients and driving anabolic processes. When nutrients are scarce, GATOR1 turns off growth signals. Our study describes how KICSTOR links GATOR1 to lysosomes ...
Once thought of as having one simple job within cells, researchers continue to learn more about the importance of organelles called lysosomes. An organelle is a small structure in a cell that is ...
IgA nephropathy (IgAN) is the most common primary glomerulonephritis and a major cause of end-stage kidney disease 1. The pathological hallmark of IgAN is the deposition of predominantly IgA1 immune ...
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