Scientists have determined the atomic crystal structure and functional mechanism of an enzyme essential for eliminating unwanted, non-nutritional compounds such as drugs, industrial chemicals, and ...

Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen that is often associated with healthcare settings but can cause serious infections in anyone. These illnesses are difficult ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 72, No. 10 (1975), pp. 4162-4166 (5 pages) During penicillin treatment of an autolysin defective mutant ...

In the cells of humans and other organisms, only a subset of genes are active at any given time, depending largely on the stage of life and the particular duties of the cell. Cells use different ...

The function of an enzyme, critical to most forms of life, has been revealed. A research team, led by the John Innes Centre found that the enzyme DNA topoisomerase VI (topo VI) performs a critical ...

WITH our present knowledge of enzyme processes any conception of their mechanism must be essentially highly speculative. In the work under notice the author makes no claim to deal comprehensively with ...

An international research team led by the University of Leicester has made a breakthrough advance by trapping an intermediate in the mechanism of enzymes called heme peroxidases and determining its ...

Fabry disease (FD) is a rare X-linked recessive glycosphingolipid-storage disorder caused by deficient activity of the lysosomal enzyme alpha-galactosidase A. Intravenous enzyme replacement therapy ...

In the human body, proteins called enzymes help speed up chemical reactions that are vital for life. After you eat, enzymes help your body break down food and obtain energy. Enzymes are also ...

The findings confirm that allosteric inhibition of integrase is clinically viable, validating a new antiviral drug class.