Acute lung injury (ALI) and its severe manifestation, acute respiratory distress syndrome (ARDS), result from direct pulmonary insults or systemic inflammatory triggers that disrupt the ...

Researchers at the University of Arizona R. Ken Coit College of Pharmacy have developed a new strategy that helps the immune ...

Suppression of chimeric antigen receptor-modified T (CAR-T) cells by the immunosuppressive tumor microenvironment remains a major barrier to their efficacy against solid tumors. To address this, we ...

A human cell culture model of the lung's most important immune cells, alveolar macrophages, helped make a key finding that is prompting researchers to rethink the role of another immune protein. A ...

A better understanding of inflammation and lung immunity over the past two decades has led to new, innovative treatments for asthma, including biologic therapies. This is especially true for a subtype ...

This novel finding, reported in the journal Nature Medicine, is important because, despite significant advances to reveal the pathological mechanisms of persistent fibrosis, effective treatment ...

Biological assailants like fungi, bacteria, and viruses continuously test natural defenses that have evolved over millennia. Newer and stranger particles that originate from burning fuels, harmful ...

A model based on proteins vs. a questionnaire had higher discrimination in predicting lung cancer risk in individuals with a smoking history, according to data presented at the American Thoracic ...

Respiratory diseases are a challenging problem to treat. Inhalable medicines are a promising solution that depend on the ability to deliver tiny particles known as aerosols to the correct location in ...

Researchers from Australia and Bangladesh have developed an artificial intelligence model capable of spotting and distinguishing between multiple types of lung disease. Called LungNet, the tool ...

Physiologically Based Pharmacokinetic Model to Assess the Drug-Drug-Gene Interaction Potential of Belzutifan in Combination With Cyclin-Dependent Kinase 4/6 Inhibitors A total of 14,177 patients were ...

Respiratory infections are among the leading causes of illness and death in the elderly, driven by immune aging, chronic diseases, and reduced physiological resilience. Pseudomonas aeruginosa, an ...