Some regions of nucleic acid targets are not accessible to heteroduplex formation with complementary oligonucleotide probes because they are involved in secondary structure through intramolecular ...

In the case of nucleic acid tests, polymerase chain reaction (PCR) has been the gold standard for single-molecule diagnosis. Single-molecule detection of pathogens, such as severe acute respiratory ...

DNA is the poster child for high-specificity binding. As long as their base sequences match, two complementary strands of DNA can navigate through a sea of biomolecules, find each other, and hold fast ...

Researchers are finding more genes directly associated with cleft lip and palate. Science X Daily and the Weekly Email Newsletter are free features that allow you to receive your favorite sci-tech ...