Ongoing elimination efforts have altered the global distribution of Onchocerca volvulus, the agent of river blindness, and further population restructuring is expected as efforts continue. Therefore, ...

Despite decades of research, scientists have yet to pinpoint the exact cause of nodding syndrome (NS), a disabling disease affecting African children. A new report suggests that blackflies infected ...

More than 21 million people in Africa are infected with the nematode Onchocerca volvulus, the cause of river blindness. Around one in ten of those affected goes blind. Parasitologists at the ...

Onchocerciasis, or river blindness, results from infection with Onchocerca volvulus. The parasite is endemic to West Africa, in both rain forest and savanna bioclimes. Several lines of evidence ...

Moxidectin, a macrocyclic lactone, is an anthelmintic drug that selectively binds to the parasite's glutamate-gated chloride ion channels. The Food and Drug Administration (FDA) has approved ...

Scientists have for the first time fully sequenced the genome of onchocerca volvulus, the parasitic worm that causes river blindness. This has allowed them to identify a number of proteins that could ...

Microfilariae of Onchocerca volvulus obtained from onchocercomas were inoculated subcutaneously into the inguinal region of mice. Microfilariae disseminated rapidly, invading the tail and lungs within ...

Tommy Leung does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond their ...