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Doctors use ejection fraction percentages to categorize left-sided heart failure. According to a 2022 article, people with HFpEF have an ejection fraction of more than 50%.
It has specific treatments depending on the type of amyloidosis, in addition to the treatments mentioned above for heart failure. Dear Dr. Roach: I am just getting over the horrible shingles.
Novo Nordisk (($DE:NOVA)) announced an update on their ongoing clinical study. Study Overview: Novo Nordisk is conducting a study titled ‘Effects ...
Overall, SGLT2 inhibitors show clear benefits in both heart failure with reduced ejection fraction (HFrEF) and HFpEF populations, while sacubitril-valsartan is emerging as an important HFpEF therapy.
Source Reference: Oraii A, et al "Atrial fibrillation ablation in heart failure with reduced vs preserved ejection fraction: a systematic review and meta-analysis" JAMA Cardiol 2024; DOI: 10.1001 ...
Solomon, S. D., et al. (2024) Finerenone in Heart Failure with Mildly Reduced or Preserved Ejection Fraction. New England Journal of Medicine. doi.org/10.1056/NEJMoa2407107.
Given the current trends, heart failure with normal ejection fraction will become the most common form of heart failure, for which we do not currently have an evidence-based successful treatment.
Mc Causland FR, Claggett BL, Vaduganathan M, et al. Decline in estimated glomerular filtration rate after dapagliflozin in heart failure with mildly reduced or preserved ejection fraction: a ...
For patients with heart failure with preserved ejection fraction (HFpEF), endovascular treatment (EVT) improves left ventricular (LV) diastolic function, according to a study published online Sept ...