The Journal of Immunology reports that vaccination of neonatal mice with group A Streptococcus promoted a clonal expansion of innate-like B cells that produce antibody against N-acetyl-D-glucosamine, ...

In the Framingham Heart Study, a prospective analysis of 189 patients who developed T2D during a 12-year follow-up compared with 189 matched controls showed differential associations between lipid ...

Patients with type 2 diabetes often have comorbid major depressive disorder, but the underlying neurobiological substrates are still poorly understood. The goal of this study was, therefore, to ...

For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining ...

Diabetic neuropathy affects a large proportion of individuals with long-term diabetes and may often go unnoticed in the early stages of the condition. As the condition progresses, severe pain and ...

Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of pancreatic β-cells. One of the earliest aspects of this process is the development of autoantibodies and T cells ...

This is a preview. Log in through your library . Abstract Increased intestinal permeability has been observed in numerous human autoimmune diseases, including type-1 diabetes (T1D) and its' animal ...

Vaccination of neonatal mice with group A Streptococcus promotes clonal expansion of B cells that produce antibody against GlcNAc. The association of reduced Type 1 diabetes risk after group A ...

I AM humbly grateful to the New England Diabetes Association for inviting me to deliver the Seventh Elliott Proctor Joslin Memorial Lecture, and to be the first person from outside the American ...