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Triggering RNA activation on demand: Strategy expands options for therapeutics and gene editing
National University of Singapore (NUS) researchers have devised a method to safely and temporarily "switch off" and then "turn on" ribonucleic acid (RNA) inside cells. This is achieved using ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, No. 5 (Feb. 27, 2001), pp. 2550-2554 (5 pages) The yeast transcriptional repressor Tup1, tethered to DNA, ...
This study illustrates a valuable application of BID-seq to bacterial RNA, allowing transcriptome-wide mapping of pseudouridine modifications across various bacterial species. The evidence presented ...
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Exploring citrullination as a key regulator of gene expression and disease
Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease. This process, driven by the enzyme ...
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