Background Systemic lupus erythematosus (SLE) shows marked heterogeneity in epidemiology across regions and over time.
Objective Limited examinations from prior studies support the absence of retinal toxicity in infants exposed to maternal ...
Objectives Lupus Low Disease Activity State (LLDAS) and Definition of Remission in SLE (DORIS) are associated with improved ...
Objective In PAISLEY, a 48-week, phase II, randomised controlled trial that assessed deucravacitinib in patients with active SLE, all primary and secondary endpoints were met with the deucravacitinib ...
Background Patients with lupus face increased cardiovascular risk linked to their autoimmune status. This study assesses the relationships between cardiovascular risk factors, lifestyle and ...
Diagnosis of SLE is based on clinical manifestations and laboratory findings. Timely diagnosis and treatment are important to control disease activity and prevent organ damage. However, diagnosis is ...
Background Interstitial fibrosis in lupus nephritis (LN) is often infiltrated by immune cells but typically regarded as non-specific ‘scar reaction’. This study aimed to investigate the relationship ...
Background Systemic lupus erythematosus (SLE) has been well known to be associated with B cell hyperactivation with overexpression of B cell-activating factor of the TNF family (BAFF). Belimumab (anti ...
Objective This study aimed to validate claims-based algorithms for identifying SLE and lupus nephritis (LN) in Medicare data, enhancing the use of the Lupus Index for geospatial research on SLE ...
Ocular involvement in antiphospholipid syndrome typically manifests as retinal artery or vein occlusions. Isolated progressive retinal microvascular impairment as associated with antiphospholipid ...
Objectives Ethnicity and health outcomes are intrinsically interrelated, although mechanisms are complex. SLE is a disease with higher incidence in Asian, Black, Hispanic and Indigenous populations ...
Objectives Patients with SLE take multiple medications. Within a large prospective longitudinal SLE cohort, we characterised medication-related hospitalisations and their preventability. Methods We ...
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