Karl-Anthony Towns likely is the player the Knicks can least do without, especially with Mitchell Robinson still unable to practice.

The Knicks' Karl-Anthony Towns (thumb) is questionable for Friday's game against the Timberwolves, who will be without starter Donte DiVincenzo (toe).

Karl-Anthony Towns of the Knicks has a bone chip in his right thumb, but is expected to try to play through the injury.

Knicks center Karl-Anthony Towns is questionable to face his former team Friday with a sprained right thumb, while Minnesota’s Donte DiVincenzo will miss his return to Madison Square Garden with a toe injury.

Donte DiVincenzo, a Knicks hero of last season’s playoffs, has been ruled out of Friday’s MSG return because of a sprained toe, the Timberwolves announced. It’ll represent the durable DiVincenzo’s first DNP of the season for the T’wolves and puts a damper on an anticipated matchup between offseason trade partners.

The Cavaliers are coming off a 20-point loss at Oklahoma City on Thursday that left the teams tied for the best record in the NBA at 34-6. Cleveland trailed by as many as 42 points in the game and G Donovan Mitchell had a season-low eight points.