Follow live coverage as Manchester United face Southampton today in the Premier League. Another top-flight season will be covered in full right here with The Independent, as reigning champions Manchester City look to make it an unprecedented five titles in a row come the end of 2024/25.

Manchester United will be without one key player for tonight’s Premier League clash against Southampton. Diogo Dalot’s two yellow cards against Arsenal in the FA Cup penalty shootout win means he serves a one-game suspension for the midweek clash at Old Trafford.

All of this week's midweek Premier League matches are set to be shown live in the UK exclusively on TNT Sports -- with the game showing on its TNT Sports 1 and TNT Sports 1 HD channels, as well as its TNT Sports Ultra channel in 4K.

Liverpool came from behind to lead against Manchester United, but the Reds gave up a second goal to drop two points in their title charge.

Prediction, kick-off time, TV, live stream, team news, h2h results, odds - Man Utd must back up a promising start to 2025 with a resounding win at Old Trafford