Predictions, picks and odds for NFL Week 16 game
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Niners Wire on MSN
Former NFL QB believes 49ers would be dangerous in the playoffs
The San Francisco 49ers currently hold a playoff spot, and at least one analyst thinks they could be dangerous if they make it.
The 49ers can clinch a playoff berth in Week 16 with a win over the Colts — or with help before kickoff. Here's how San Francisco gets in.
Obviously, the one seed is what the 49ers are aspiring for. It gets you a bye week, and the team that may want a bye week the most is the 49ers. If they can get a little more rested for some of their injured defenders and Ricky Pearsall, it would go a long way. They draw the bottom seed the rest of the way, which helps as well.
This is a great NFL matchup that you will not want to miss; make sure to tune in and catch all the action. Fubo offers a free trial, and you can watch the NFL on local CBS and FOX broadcasts every Sunday. You can also live stream NFL RedZone and catch football all season long on CBS, FOX, ESPN, NFL Network, and more.
NBC Sports Bay Area on MSN
Where 49ers star players stack up in final round of 2026 NFL Pro Bowl fan voting
San Francisco 49ers stars Christian McCaffrey and Kyle Juszczyk both sit atop their positions in Pro Bowl fan voting.
After playing his first NFL game in almost five years on Sunday, Philip Rivers will remain at quarterback for the Indianapolis Colts’ next contest in a prime-time appearance. The Colts play the San Francisco 49ers at 7:15 p.